Crypt neurons are olfactoryreceptor cells located in the olfactory epithelium of fishes.
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Electrophysiological activities of olfactoryreceptor neurons in intact epithelium were measured through the multi-channel recording system.
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More recently, odorants have also been shown to affect the levels of cGMP in olfactoryreceptor neurons.
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How is activation of such a subpopulation of olfactoryreceptor neurons in the periphery sensed by the brain?
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However, other scientists think DEET acts directly on an as-yet-unidentified olfactoryreceptor, irritating them instead of just hindering them.
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Here, we outline a conceptually different strategy in which we search for odorantreceptors activated by a known odorant.
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Subsequently, single cell RT-PCR is used to reveal the identity of the odorantreceptors expressed in retrogradely labeled neurons.
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RNA levels of all class I, class II, and TAAR odorantreceptors are markedly reduced in OSNs in a non-cell autonomous manner.
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Here we wished to investigate, whether the principle of spatial segregation observed for odorantreceptors extends to another olfactory receptor family, the V2R-related OlfC genes.
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Odorantreceptors belong to class A of the G protein-coupled receptors (GPCRs) and detect a large number of structurally diverse odorant molecules.